Jimmy Fallon is taking the night off.
A rep for NBC tells ET that Friday's taping of The Tonight Show Starring Jimmy Fallon has been canceled "due to a private Fallon family matter." Instead, a repeat of Sept. 25's episode with Madonna and Camila Cabello will air.
A source tells ET that the late night host's mother, Gloria, is sick and in the hospital.
"Jimmy comes from a very close-knit family, and together with the rest of his loved ones, they are by her side right now," the source explained.
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No production changes for next week are planned at this time.
Just last month, Fallon opened up to ET about his family and raising two young daughters. Watch the video below.