No matter what she's doing onstage, Madonna is always a natural.
On Tuesday night, the 59-year-old singer showed up with Amy Schumer to the Comedy Cellar in New York City, and put on quite a show.
"And the next minute, I was tagging along with @amyschumer at @nyccomedycellar making my stand-up debut!" she captioned a photo on Instagram of herself onstage with the comedian. "What a thrill. Finally busted my cherry.??? Thank you, Amy!"