This 1981 classic by director John Landis broke new ground, mixing horror with comedy and never-before-seen lycanthrope transformations and makeup effects that not only earnedRick Baker his first Academy Award, but also helped generate a brand-new category: Outstanding Achievement in Makeup. David Naughton and Griffin Dunne play buddies backpacking through Europe who are attacked by a werewolf on the British moors. David wakes up in a London hospital, while Griffin wakes up dead – but that doesn't stop him from haunting his pal and warning him of the impending full moon. Will David sprout fangs and run about on all fours, or is it all in his mind?