'A Million Ways' Stars Seth & Charlize Turn Tables on ET!

Seth MacFarlane skewers the Old West in his outrageous new comedy A Million Ways to Die in the West, and ET special correspondent, Oxygen Media's Susie Castillo, is with Seth and co-star Charlize Theron to talk up the movie – and try to get a little insight into Charlize's public romance with Sean Penn. That is, until Seth turns the tables on Susie! Watch the fun video…

The follow-up to his raunchy hit comedy Ted, Seth directs, produces, co-writes and plays the lead role in A Million Ways to Die, which follows the exploits of a cowardly sheep farmer who must find his courage after he backs out of a gunfight and his girlfriend (Amanda Seyfried) leaves him. When a mysterious and beautiful woman (Charlize) rides into town and helps him regain his mojo, the two fall in love -- and now he's tasked with confronting her notorious outlaw husband (played by Liam Neeson)! With a million ways to die in the west, can he survive just one more day? Giovanni Ribisi, Neil Patrick Harris and Sarah Silverman, Wes Studi, Gilbert Gottfried, Bill Maher and Christopher Lloyd also star.

Related: Charlize Theron Teaches 'Model Face' in 'SNL' Promos

If Seth and Charlize could go back in time and tell their younger selves something that they know now, what would that be? "Buy stock in Apple," says Seth, while Charlize muses, "I would tell myself about a few guys to not date."

A Million Ways to Die in the West is in theaters now.