Stars Gear Up for New 'Stand Up to Cancer' Show

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Gwyneth Paltrow is taking the helm of this year's Stand Up To Cancer show, which organizers promise will be another historic star-studded affair to raise money for cancer.

"This broadcast has become a global call-to-action for all those touched by cancer," said Paltrow, executive producer of the show, which will air live from the Shrine Auditorium in Los Angeles on September at 8 p.m. "Like so many people, I know what it's like to lose a family member to this disease, and I'm honored to stand up in my father's memory," the actress said.

The show is groundbreaking because it is broadcast simultaneously by all the major television and cable networks -- reaching millions of viewers worldwide. The show's incredible star power helps build public support and raise funds for the latest research efforts aimed at accelerating the delivery of new therapies to cancer patients.

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The first two Stand Up to Cancer telecasts took place on September 5, 2008 and September 10, 2010, and were viewed in more than 190 countries. To date, more than $180 million has been pledged for the organization's innovative cancer research programs.

Among past stars to participate in the broadcasts were Jennifer Aniston, Christina Applegate, Lance Armstrong,  Halle Berry, Beyonce, Jack Black, Mary J. Blige, Josh Brolin, George Clooney, Reese Witherspoon, Sheryl Crow,  Ellen DeGeneres, Michael Douglas, Jennifer Garner, Jim Parsons, Ryan Seacrest, Will Smith, Stevie Wonder, Meryl Streep and many others.

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