Online reports claim the actor, 49, pulled a knife on a dental technician while under the influence of rock cocaine, but Sheen's rep Jeff Ballard tells ET that the allegations are false.
"There was no knife and no one inside Charlie's camp has heard from the LAPD," Ballard said.
The rep admitted that Charlie was taking medication for a shoulder injury at the time of the alleged incident, but he denies that Charlie used illegal substances.
This news follows Charlie's expressed interest in returning to Two and a Half Men as it nears its series finale.
"I've reached out to them and they've reached back," Sheen told TV Guide Magazine in September. "We're trying to figure out what makes the most sense. If they figure it out like I've presented it to them and they want to include me in some final send-off, I'm available and I'm showing up early. If not, it's on them."
Sheen notoriously exited the show in 2011 after a war of words with executive producer Chuck Lorre. It's not clear how his character Charlie Harper would be brought back, as he was killed off the show.
This past summer, Sheen was videotaped telling a Taco Bell drive-thru employee that he was "f**king hammered," which can be seen in the video below.