Green alleges that statements made by Cosby's lawyer, claiming Green's rape allegations were "absolutely false," have hurt her reputation by branding her as a "liar."
According to the lawsuit, filed in Springfield, Mass. -- not far from Shelburne Falls where Cosby owns a house -- the Cosby Show star's lawyers have allegedly attempted to publicly expose Green to ridicule and contempt.
Green's lawyer, Joseph Cammarata, told People that his client was filing the suit in an attempt to "restore her good name and reputation."
"That's all we've got in life at the end of the day," Cammarata said. "It's the most important thing we have."
In November, one of Cosby's lawyers, Walter M. Phillips Jr., issued a statement to The Washington Post which read, in part, "Mr. Cosby does not know the name Tamara Green or Tamara Lucier [her maiden name] and the incident she describes did not happen."
Cosby's lawyers have not yet publicly responded to Green's defamation lawsuit.
Green first went public with her sexual assault allegations in 2005 in the wake of claims made at the time by another woman, Andrea Constand.
Green alleges that in 1975, she had dinner with Cosby, who gave her pills that he claimed would help with her flu-like symptoms, but soon after she was nearly unconscious. Green went on to claim that Cosby took her back to her home, undressed her and began groping her.
Green spoke out again in November, writing an op-ed for ETonline, which detailed the blowback she claims to have suffered since coming forward with her allegations.
"To go for help and be dismissed because [Cosby is] very cool and famous and you are not," Green wrote. "It is crushing, and you are a victim all over again."
Cosby has not been charged with any crime and his attorney has denied all claims against him.
A number of women have come out in recent months, accusing Cosby of sexual assault and rape. Three of these accusers, Beth Ferrier, Helen Hayes, and Chelan, sat down with ET to discuss their allegations. Watch the video below to see more.