Joan Vollero, a spokesperson for the Manhattan District Attorney's Office, said there was not enough evidence to support any charges.
"This case was taken seriously from the outset, with a thorough investigation conducted by our Sex Crimes Unit," Vollero said in a statement to ET. "After analyzing the available evidence, including multiple interviews with both parties, a criminal charge is not supported."
The 22-year-old woman claimed that Weinstein, 63, had persuaded her to meet him at his Manhattan office under the pretext that they were to talk business and then groped her breast during the meeting.
Weinstein has been married to British designer Georgina Chapman, 38, for seven years. The couple shares two children together: two-year-old son Dashiell and four-year-old daughter India.