The mashup between the two very different genres turned out to be a great fit, as one of the biggest acts in country and one of the hottest stars of in the world of electronica delivered a raucous performance that could lead to a whole new wave of cross-genre Country EDM.
In fact, Lady Antebellum spoke with ET on the red carpet before the show, and hinted that there are a few more cross-genre mashups on the horizon.
"It's a little bit of a preview," Lady Antebellum singer Hillary Scott said. "We've got a song coming out later this summer with another DJ his name is Audien."
"This is just our first kind of step into this world and who knows if we'll ever step back into it but it is sure fun to do something totally different than we've ever done before," Scott added.
Zedd and Lady Antebellum's team-up was a great way to kick off the night. However, Lady A got even more love later on when they took home the CMT Music Award for Group Video of the Year for their song "Bartender."