Speaking with a reporter during on the red carpet at a screening of his upcoming drama The End of the Tour, Eisenberg compared the massive pop-culture convention to "genocide," the Associated Press reported.
"It is like being screamed at by thousands of people. I don't know what the experience is throughout history, probably some kind of genocide. I can't think of anything that's equivalent," Eisenberg said when asked about his experience at Comic-Con.
His off-hand remarks about his experience offended some who didn't appreciate how his comments seemed to diminish the tragedy and horror of genocide.
According to the AP, Eisenberg attempted to clarify his remarks during an interview alongside his The End of the Tour co-star Jason Segel.
"Maybe on some cellular memory level, that's the only thing that seems like an equivalent social experience," Eisenberg explained. "Even if [fans] are saying nice things, just being shouted at by thousands of people, it's horrifying."
In an attempt to further explain himself, the Social Network star reportedly reached out to the AP a third time, explaining, "I of course was using hyperbole to describe the sensory overload I experienced. I sometimes do employ that… I'm a normal person who has normal sensory experiences, so Comic-Con was very overwhelming for me."
Eisenberg, who stars as iconic villain Lex Luthor in the highly anticipated Batman v Superman: Dawn of Justice, went on to say that he actually felt that it was "an honor to be on that end of such jubilation."
"I've been on the receiving end of movies that no one loves and no one anticipates," Eisenberg said. "That's worse, even though it's a much quieter press tour."
For a look at Eisenberg's role as Lex Luthor, which landed him at Comic-Con alongside his co-stars Ben Affleck, Henry Cavill and Jeremy Irons, among others, check out the brand new trailer for Batman v Superman: Dawn of Justice in the video below.