Gaga opened up about how sexual assault has 'tormented' her family for years.
Lady Gaga made a special appearance at the Producers Guild Awards in Culver City, California on Saturday where she performed for the star-studded audience.
The six-time GRAMMY winner sang her Oscar-nominated single, "Til It Happens To You," from the soundtrack to the documentary The Hunting Ground, which details the harrowing subject of college campus rape.
Gaga got candid during her performance, opening up about her own life, and the lives of her family members who have been impacted by sexual assault.
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"It's not only an important issue to me, but it's an important issue to my family because when my father's sister was in college, she was sexually assaulted," said Gaga (via People). "Then, it tormented her so emotionally that it caused the lupus that she had to get so bad that she died."
She went on to explain how the incident "affected my family really tremendously" and that the tragedy became "one of the centerpieces of our family."
"So this song means so much to me and so much to my parents," Gaga said.
WATCH: Lady Gaga Confronts Campus Rape in Powerful, Graphic 'Til It Happens to You' Music Video
The 29-year-old singer has opened up in the past about being the victim of sexual assault herself.
During an interview with Howard Stern in December 2014, Gaga said that her song "Swine" was about rape, and revealed that she was victimized when she was 19 years old, but that she wasn't willing to discuss the event publicly for years because she didn't want to let it define her or her music.
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At the PGAs, Gaga went on to thank Dianne Warren, with whom she co-wrote "Til It Happens To You." The singer was also joined at the ceremony by her fiancé, Taylor Kinney.
Mother Monster will be in heated competition at this year’s Oscars, which has come under fire for the lack of diversity among those nominated in the acting categories. Academy of Motion Picture Arts and Sciences President Cheryl Boone Isaacs was also a guest at the PGAs, and spoke with ET about the Academy’s plans to promote diversity in the future. Check out the video to hear more.