EXCLUSIVE: Lana Wachowski on Coming Out: 'Once You Accept Who You Are, You Will Always Be More Free'

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Lana Wachowski, one half of The Matrix trilogy filmmaking siblings The Wachowskis, has some pretty sound advice to those coming out as transgender.

On Tuesday, Lana's younger sister, Lilly Wachowski, officially came out as transgender in a statement to Chicago's Windy City Times. The news comes nearly four years after Lana made her first public appearance as a transgender woman in July 2012, and later spoke publicly about her transition while accepting a Human Rights Campaign award in October of that same year.

Last February, ET spoke with Lana at theJupiter Ascending premiere. The 50-year-old director talked about coming out as a transgender in Hollywood when asked if she had any advice for Caitlyn Jenner.

NEWS: Second Wachowski Sibling Comes Out as Transgender

"I say, you have to be true to yourself," Lana exclusively told ET. "When you encounter people, whether they're racists or they're homophobic or their transphobic, what you realize is that those people are actually more controlled by social convention than you are."

"In a way, once you accept who you are, you are will always be more free than they are," she continued.

In her statement on Tuesday, Lilly, 48, said she decided to go public after she claimed she was recently confronted at her home by a reporter from the Daily Mail. Lilly said that although she and her sister have "largely avoided" the press in the past, she "knew at some point I would have to come out publicly."

"You know, when you're living as an out transgender person it's … kind of difficult to hide," Lilly wrote. "I just wanted -- needed -- some time to get my head right, to feel comfortable. But apparently I don't get to decide this … So yeah, I'm transgender. And yeah, I've transitioned."

"Everyone is cool with it," she said of her friends and family, and her wife, Alisa Blasingame, who she's been married to since 1991. "Yes, thanks to my fabulous sister they've done it before, but also because they're fantastic people. Without the love and support of my wife and friends and family I would not be where I am today."

In a statement to ET on Wednesday, the Daily Mail "categorically denies that it in anyway tried to coerce Lilly Wachowski into revealing her gender transition."

WATCH: Transgender Women Share Their Personal Stories With ET Correspondent Janet Mock

Last July, Caitlyn, 66, revealed her own "tipping point" for coming out as transgender.

"I was growing up in a very different time and I had no information," Caitlyn wrote in her blog. "Meanwhile, I had all of my diversions -- sports...this...that...married...family -- but after 65 years, here I was right back with the same problems that I had when I was 10 years old and I had to finally do something about that."

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