The 41-year-old actress and husband Will Kopelman have called it quits after three years of marriage.
Drew Barrymore and Will Kopelman has called it quits after three years of marriage.
While the former couple, who are parents to two young children, has had some incredibly sweet moments during their time together, the Donnie Darko star has opened up about her challenges with marriage in the past.
WATCH: Drew Barrymore and Will Kopelman Split After 3 Years of Marriage
Here are seven things she's said about love, and her own experiences with struggle in married life.
1. Her Relationship With Kopelman 'Was Never Really Love at First Sight'
In October, which is around the time a source first told ET that talk of a separation had begun, Barrymore candidly admitted some of the struggles she and Kopelman had.
"It was never really love at first sight," Barrymore told InStyle at the time. "Will struck a lot of my pragmatic sides. He was someone who was always reachable on the phone, someone who was a classy human being, someone who had this incredible blueprint of a family that I don't have."
"At the same time, what I love about him is that he embodies the power of choice," the actress added. "He chooses to be a good person every day."
2. 'We're Polar Opposites. It's Still Really Hard'
During the same interview, Barrymore did not sugarcoat the challenges she and Kopelman were going through as a couple.
''We've made many compromises and concessions, but when it comes to how we deliver likes and dislikes, we're polar opposites," she said. "It's still really hard."
WATCH: Drew Barrymore’s Gets Tattoo on Her Wrist for Daughters Olive and Frankie
3. She Revealed She Was 'Trying' to Hang in There With Her Husband
While talking to Howard Stern on his Sirius XM radio show in October, Barrymore was forthcoming about the challenges of marriage "when you have kids," adding, "they love his family."
When Stern pressed the actress on whether she would "hang in there" with Kopelman, she responded she was "trying."
4. Her 'Perfect and Totally Imperfect' Family Life
After giving birth to Olive, Barrymore revealed that she suffered postpartum depression for a period of six months. Describing her family life as "perfect and totally imperfect," the director and actress said that the couple's focus at the time was squarely on their children over their own relationship.
"Honestly, I don't know how it is for other couples but really I like watching him be a father," Barrymore told People in October. "I know everyone says you're supposed to put your coupledom first. But I really love it being all about the kids. Maybe that's my compensating for not having parents myself or a childhood but right now, the focus is about how we're figuring things out as parents."
5. She Spoke About the Importance of Compromise
"I think a good place to start is when a significant other points things out that are tough for them and they are things that you're willing to change in your life," Barrymore told Us Weekly in November. "If you really said, 'Why am I fighting for this?' Start with those. My husband used to tell me, 'I hate that we're always racing to the airport. It's like an anxiety attack.' And I thought, 'Yeah, why am I fighting for that?' I don't like anxiety, so now I pack the night before."
"Compromise is about changing yourself for the better," she added. "It's an opportunity for you to become a more functional, better person."
6. She Believes 'Acceptance of the Entire Being of Another Person' Is Imperative
"...We have to change for the better to grow as a couple," Barrymore added in the same interview, noting that "acceptance of the entire being of another person" is key.
PHOTOS: Stars Share Pics of Their Cute Kids
7. Her Marriage to Kopelman Gave Her a Little Piece of the Childhood She Never Had
"I won the in-laws jackpot. It might be the best karma for having one of the wackiest upbringings," Barrymore told C magazine in 2013, a year after marrying Kopelman.
"I never had dinner with my mom or dad, let alone together. It's amazing to think that in life you can completely have a do-over."
MORE: Drew Barrymore on Childhood: 'I Didn't Really Have Parents'
It's clear that throughout her marriage, Barrymore remained positive while still being honest to herself about the troubles in her relationship.
Watch the video below.