Osbourne looked upbeat as she happily walked the red carpet, despite her parents' divorce drama. The purple-haired beauty was all smiles while posing for photos with her adorable Pomeranian nestled safely in a Louis Vuitton carrying case.
Before the night's festivities got under way, Kelly shared a glam shot on Instagram wearing "half a million dollars of punk rock jewelry!"
The black-tie benefit celebrating men in fashion was hosted by Whoopi Goldberg and raised $1.2 million for amfAR's AIDS research initiatives. Other celebrity attendees included Naomi Campbell, who was honored for their longtime commitment to the battle against AIDS, Leonardo DiCaprio, Zayn Malik, Dwyane Wade, Gabrielle Union, Victoria Justice, Jason Derulo, and amfAR chairman of the board, Kenneth Cole.
Kelly isn't the only celeb to bring her pooch to a high-profile event. Carrie Fisher brought her French bulldog to the White House Correspondents' Dinner last month, where he walked the red carpet with his famous mom and actor Tom Hiddleston.
Watch what happened when Serena Williams tried her dog's food in the video below.