EXCLUSIVE: Snoop Dogg and Seth Rogen Team Up for a Good Cause at 5th Annual Hilarity for Charity Variety Show

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The beloved rapper is set to perform live as the star-studded event's musical headliner.

Seth Rogen is bringing some musical star power to this year's fifth annual Hilarity for Charity Variety Show, recruiting rapper Snoop Dogg to headline the Halloween-themed event.

The "Young, Wild and Free" musician is set to perform several songs throughout the evening at the star-studded event, which is put on annually by Rogen and his wife, Lauren Miller Rogen, to benefit the Alzheimer's Association.

"Each year, we set out to plan a show that will entertain and make people laugh. With Snoop as our headliner, I think we can guarantee our audience a pretty incredible evening! We can’t wait to see what he has cooked up," the Neighbors star said in a statement to ET.

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The 44-year-old rapper said he "didn’t think twice" about signing on to perform for a good cause.

Rogen and his wife founded the Hilarity for Charity Fund four years ago, with all proceeds going to help families affected by Alzheimer's and towards research into groundbreaking methods for combating the illness that impacts millions of people around the world. Since its creation, the event has raised over $5 million to help fund these initiatives.

Snoop Dogg joins the ranks of Hilarity for Charity’s past musical guests like The Backstreet Boys, Bel Biv Devoe, Bruno Mars, Mayer Hawthorne and Miley Cyrus.

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When the "Wrecking Ball" singer rocked the charity gala last year in a wildly revealing outfit, the theme was "James Franco's Bar Mitzvah," and Cyrus helped the star honor his manhood with such karaoke favorites like "Super Freak" and "Shout." Check out the video below to see more from the wild night of fundraising.

Those interested in a chance to attend this year’s event as VIP guests can donate to HFC through their CrowdRise Campaign. For more information and to purchase tickets, check out the organization online at www.hilarityforcharity.org.