"Lipstick Jungle" is coming to Thursday nights.

NBC is trading Chicago's emergency medical staff for a trio of NYC power women when the network launches its mid-season schedule.

BROOKE SHIELDS leads a trio of successful ladies in "Lipstick Jungle," which will replace "ER" in the Thursday night timeslot starting February 7.

It will be the first time another show airs in the coveted spot since "ER" made its debut in 1994. The long-running drama is being put on hiatus due to the ongoing writers strike.

The highly anticipated new series, which also stars KIM RAVER and LINDSAY PRICE, is a comedy-drama based on the novel of the same name by "Sex and the City" scribe CANDACE BUSHNELL.