It's "Rocky Mountain High" for Oprah and Tom Cruise, pictured here in Colorado.

OPRAH WINFREY goes one-on-one with TOM CRUISE on her Friday, May 2 "The Oprah Winfrey Show," filmed on location at Tom's home in Telluride, CO. The two are shown here on location.

Then, on Monday, May 5, the talk show queen and the "Mission: Impossible" star will celebrate his 25 years in film since his breakout role in 'Risky Business.' Monday's show will broadcast from Oprah's studio in Chicago.