Talking dog flick 'Beverly Hills Chihuahua' led the box office for the second week running, taking in $17.5 million, according to preliminary studio estimates.

The film about a posh Beverly Hills chihuahua who finds herself lost while on vacation in Mexico and seeks help to return home stars Drew Barrymore, Jamie Lee Curtis, Andy Garcia and George Lopez.

Horror pic 'Quarantine' debuted at No. 2 with $14.2 million. "Dexter"'s Jennifer Carpenter stars as a TV reporter whose routine fire department ridealong turns into a living hell when she is trapped inside a mysteriously quarantined apartment building to deal with unspeakable horrors.

Leonardo DiCaprio and Russell Crowe's Iraq war thriller, 'Body of Lies,' premiered in third with $13.1 million. In 'Body of Lies,' Leo and Russell play CIA operatives who team up to track an al-Qaeda leader rumored to be planning attacks against America. Leo's character is an ex-journalist-turned-CIA agent who is sent to Amman, Jordan, to work with an intelligence chief, played by Russell.

Shia LaBeouf's thriller, 'Eagle Eye,' dropped to fourth with $11 million, while dramedy 'Nick and Norah's Infinite Playlist' (starring Michael Cera and Kat Dennings) fell to fifth with $6.5 million.