Jessica Biel is making a difference in the lives of some very special children!

Jessica and her family started the Make The Difference Network (MTDN), which connects nonprofit organizations with potential donors -- and increases awareness for nonprofit organizations. As part of their mission, she and the MTDN are spreading holiday cheer to kids at Childrens Hospital Los Angeles!

The event is filled with fun activities for the kids, where they get to decorate their own cupcakes, design holiday cards, decorate a Christmas tree, light the electric Menorah and take their picture with Santa!

Each child will also receive a holiday gift and there will be surprises and special celebrity guests, such as Alex Band of The Calling -- who will perform for the kids -- while actor Tyler Hilton's foundation TH Books will present an generous donation of books for the hospital's library.