Tom Hanks and wife Rita Wilson rounded up a few of their famous friends Tuesday night, including William Shatner, "Mad Men" star Jon Hamm, Alicia Silverstone and Annette Bening, to stage a one-night-only presentation of the Pulitzer-prize-winning Broadway comedy You Can't Take It With You for a great cause, and ET was there!

Held at UCLA's prestigious performing arts theater, the event marked an acting reunion for Tom and Rita with their 'Sleepless in Seattle' director Nora Ephron, who helmed the evening's production.

"One Night Only…With a Little Help From Our Friends" marked the debut of an annual gala to benefit The UCLA School of Theater, Film and Television.

Watch ET for more highlights of Tom and Rita's fun event!