ET has the details...

How will the "Oprah Winfrey Show" celebrate Barack Obama's inauguration? ET's got the 411!

Oprah is taking her show to Washington D.C. for a two-day special event. First, on Monday, Jan. 19, the show will broadcast from the world-famous Kennedy Center Opera House. Oprah's special guests include Demi Moore and Ashton Kutcher, plus a group musical performance by Bono, Will.i.am, Faith Hill, Seal, David Foster and Mary J. Blige, who will sing a brand new-song marking the historic occasion.

Then, on Wednesday, Jan. 21 -- the day after the inauguration -- "Oprah" will air live from chef Art Smith's "Art and Soul" D.C. restaurant, where Lady O will be joined by Forest Whitaker, Jon Bon Jovi and Gayle King.