Long-running daytime drama "As the World Turns" will end its run on CBS after 54 years in September 2010.

"Throughout our history, 'As the World Turns' has remained dedicated to sharing compelling stories that have entertained fans for more than five decades," said executive producer Chris Goutman. "We are disappointed and saddened by the news that the show is not being renewed. It will certainly be a loss for all of us, and for the show's loyal audience."

"'As The World Turns' has been a cornerstone of our business and a tremendous asset to the company," said Brian T. Cahill, Senior Vice President and Managing Director, TeleNext Media, Inc. "We are proactively seeking a new outlet to carry the show, and are open to exploring innovative formats and relationships that will enable the future success of 'ATWT.'"

"As The World Turns" has been entertaining generations of fans for more than half a century with its multi-generational stories. The show boasts a well-loved cast, including actress Helen Wagner (Nancy Hughes) who spoke the first words on the premier broadcast of "ATWT" in 1956. To this day, Nancy is still at the helm of the Hughes family, earning Wagner the distinction of portraying the longest-running character in television history.

Other veteran cast members still on the show today include Eileen Fulton (Lisa Grimaldi) and Don Hastings (Dr. Bob Hughes) who each have played their characters for 49 years; Marie Masters (Dr. Susan Stewart) with 41 years; and Kathryn Hays (Kim Hughes) who has starred on the show for 37 years.

In addition, the soap has launched the careers of stars such as Dana Delany, James Earl Jones, Julianne Moore, Parker Posey, Meg Ryan, and Marisa Tomei.

Created by daytime legend Irna Phillips, "As The World Turns," set in the fictional Midwestern town of Oakdale, airs weekdays on CBS.