Kathie Lee Gifford made a particularly cringe-worthy on-air gaffe in May 2012, when she asked Short about his relationship with his wife, Nancy, who actually died in 2010 of ovarian cancer.
"You and Nancy have one of the greatest marriages of anybody in show business," Gifford said. "How many years now for you guys now?"
"We … married 36 years," Short replied.
"But you're still in love!" Gifford remarked.
"Madly in love," Short kindly answered. "Madly in love."
Gifford continued, asking, "Why?" to which Short shrugged his shoulders.
"Cute. I'm cute," he said.
Gifford was made aware of her error during a commercial break.
"Martin just told me as he was leaving, he said, 'Kathie, you probably didn't know,' but his beautiful, precious wife, Nancy, did pass away a year and a half ago of ovarian cancer," she said. "I feel so badly."
Gifford later apologized on Twitter.
"I send my sincerest apologies to @MartinShort and his family," she wrote. "He handled situation w/enormous grace and kindness and I'm so grateful."