One of last season's cliffhangers was the drunken makeup session between Penny (Kaley Cuoco) and Raj (Kunal Nayyar).
"Raj gets the wrong idea that there's a spark there," Kaley blurted when asked what would transpire between the two characters following their passionate dalliance.
And then of course there's Sheldon (Jim Parsons) and Amy (Mayim Bialik), who have been making baby steps in their relationship.
"I really do love the way it's been going," Jim admitted.
"I'm thinking of it like planets revolving around each other," said Mayim. "Like, sometimes we get closer but it's still that same orbit that is very far."
And let's not forget Howard (Simon Helberg) and Bernadette's (Melissa Rauch) planned trip to the altar.
"Maybe the wedding will happen, maybe it won't," said Melissa.
"It seems like every step that happens there's just like a horrible obstacle in the way," Simon added, going on to list Howard's mother as the biggest road block of them all.
Tune in for the season premiere of The Big Bang Theory tonight on CBS.