This Is What the 'Grey's Anatomy' Cast Looks Like 10 Years Later

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Photo: ABC
Ten years, 11 seasons, and countless medical traumas, death scares, bomb threats, plane crashes, near-drownings, gunmen, weddings, babies, tears, and hospital hook-ups ago, we checked into Seattle Grace. Today, March 27, is the official 10-year anniversary of Grey’s Anatomy.
Here are the only five original characters still on the show in 2005 and now:
Ellen Pompeo as Meredith Grey
Photo: ABC
Patrick Dempsey as Derek Shepherd
Photo: ABC
Justin Chambers as Alex Karev
Photo: ABC
Chandra Wilson as Miranda Bailey
Photo: ABC
James Pickens Jr. as Richard Webber
Photo: ABC
The rest of the original cast have left since Grey’s for other opportunities:
Sandra Oh as Cristina Yang
Photo: Warner Bros. Pictures
Oh left Grey Sloan Memorial Hospital after season 10 in 2014 and has since appeared in Melissa McCarthy’s maligned comedy Tammy.
Katherine Heigl as Izzie Stevens
Photo: NBC
Heigl left during the sixth season to make a handful of bad rom-coms and now stars as CIA analyst Charlie Tucker on State of Affairs.
T.R. Knight as George O’Malley
Photo: CBS
Knight was killed off at the end of season five and has since done a guest arc on The Good Wife and starred in the failed Amazon pilot, Hysterical.
Isaiah Washington as Preston Burke
Photo: The CW
Washington was fired in season three -- though he did return for an episode in the 10th season -- and now plays Chancellor Thelonious Jaha on The 100.
Find out why the Grey’s Anatomy actors would be horrible doctors in real life: