"I know all of you came to see Ellen so I’m gonna do my best to make you very happy," Cyrus, 23, said at the start of the show after dancing out onto the stage in a pitch-perfect impression of DeGeneres' typically enthusiastic entrance. "I’m dressed like her, I smell like her, [and] just before I came out here I actually kissed a girl!"
DeGeneres had to take the day off after coming down with an illness, but her replacement couldn't have been more excited for the opportunity to host the comedian's popular program.
"Thank you guys for making me feel so welcome," Cyrus told the cheering crowd. "I’ll admit I’m a little bit nervous because I’ve never hosted a show with my clothes on before so this is so weird!"
The "Wrecking Ball" singer had to address the reason behind DeGeneres' absence, sharing, "Don’t worry you guys Ellen will be fine, but she just isn’t feeling well."
"I gave her a bunch of Molly to make her feel better," Cyrus joked. "It’s working."
Cyrus has been hitting the interview circuit herself in recent weeks after joining Adam Levine, Blake Shelton and Alicia Keys as a coach on NBC's The Voice. Check out the video below for a look at Cyrus' boisterous debut on The Voice's season 11 premiere.