After replacing Michael Strahan as the permanent Live co-host in May
, the 42-year-old TV personality did the show for the first time without Kelly Ripa by his side. Instead, he was joined by So You Think You Can Dance
host Cat Deeley, who helped him interview 50 Cent and Marisa Tomei. Meanwhile, Ripa was on vacation in Vancouver, Canada, with husband Mark Consuelos and their children.