The actress' ensemble perfectly complemented her burgeoning belly as she thanked her family during her speech.
"To my parents and my husband and my son, the most important people in the world to me," she said, referring to husband Benjamin Millepied and the couple's first child, Aleph. "Thank you so much."
Portman's recognition for her role is sure to be just the beginning, as the show's host, T.J. Miller, even called her out earlier in the night for her great work by hilariously imitating the actress (the sincerest form of flattery, obviously) in a Jackie-inspired costume.
"I was going to ask her who wore it best. Clearly she did," he joked, before spotting Portman in the crowd. "Your performance of Jackie in Jackie was just – it reminded us of what incredible leaders women can be, are, and will continue to be. I just thought it was amazing."
But back to Portman's good luck charm -- the actress previously won the Best Actress Oscar in 2011 for Black Swan when she was pregnant with her first child, and recently opened up to ET about the coincidence of current Oscar buzz for Jackie while pregnant for the second time.
"I think they're good luck charms in life," she said. "They're the best things. The best main miracles."
"I don't necessarily connect it [to winning an Oscar]," she added. "But it is certainly a joy."