Former "Celebrity Apprentice" contestant Star Jones tweeted "Sad…nice people…no joy in other's sad news."
Actor Joey Lawrence tweeted "My Heart goes out to @MarcAnthony and @jlo and their family. It's a bummer to hear."
Kimora lee Simmons sent out condolences for the couple from her and husband Djimon Hounsou. Simmons tweeted "@djimonhounsou + I send our LUV 2 lovey @jlo + @MarcAnthony n this time + always! Stay Strong!"
Actress Alyssa Milano tweeted "Anyone else really upset about JLo and Marc Anthony splitting? #SadFace."