Stand Up To Cancer: Jennifer Aniston, Ariana Grande, Rob Lowe & More Join the Cause!

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Some of your favorite stars are once again uniting to support Stand Up To Cancer (SU2C) for a telecast airing Friday.

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Among those expected to attend are Gwyneth Paltrow, Reese Witherspoon, Pierce Brosnan, Jennifer Aniston, Halle Berry, Jon Hamm, Kiefer Sutherland, Ben Stiller, Will Ferrell, Mark Harmon, Rob Lowe, Eric Stonestreet, Danny McBride and Kareem Abdul-Jabbar.

Viewers will be treated to special performances by The Who, Jennifer Hudson, Lupe Fiasco with Common, Ariana Grande and Dave Matthews.

These stars join many others who have helped out in the past, including Mark Harmon, who gave us a behind-the-scenes look at his PSA last year.

The show will stream live on Hulu and Yahoo!, while CBS, ABC, FOX, NBC and 27 other networks will donate one hour of simultaneous commercial-free primetime for the event airing Friday, September 5 at 8 p.m. ET & PT / 7 p.m. CT.