In an interview with Loaded magazine, the 42-year-old Gone Girl star says that it was Garner's love and support that is responsible for his career turnaround, but that he doesn't think audiences want to see them co-star in a movie any time soon.
"My wife and I made Pearl Harbor and Daredevil," Affleck joked. "With our track record, I don't know if anyone's looking for a three-quel."
As a matter of fact, Affleck hasn't had a great track record co-starring alongside any actress he's involved with. In the Oscar-winner's biggest critical and commercial flop, the 2003 romantic comedy Gigli, he appeared opposite Jennifer Lopez, who he began dating during filming.
And just three years prior, Affleck starred in the poorly-received 2000 romantic drama Bounce with his then-girlfriend Gwyneth Paltrow.
Affleck, who tied the knot with Garner in June 2005, credits her with helping him out of his career slump.
After a string of poorly reviewed films, Affleck delivered a celebrated performance in the 2006 historical crime drama Hollywoodland. The next year, Affleck released his directorial debut Gone Baby Gone, which found universal acclaim. In 2012, Affleck's film Argo, which he directed and starred in, won the Oscar for Best Picture.
"Getting to know Jennifer, falling in love with her and being connected with her gave me a foundation to reach out and say, 'Okay, I'm going to do Hollywoodland. I'm going to direct Gone Baby Gone,'" Affleck told the magazine. "Those were the steps forward I needed to put positive stuff on the board."