Reese's 16-year-old daughter, Ava Phillippe, also joined in on the birthday fun and shared a sweet message for her mom, writing, "Happy birthday to this lovely woman! thanks for always being there to support me. have the best day."
Reese made sure to thank all her friends and loved ones in a birthday collage on Instagram Wednesday, with the caption, "Awww...Y'all are the sweetest!! ? THANK YOU SINCERELY for all the birthday love! ?? #MakingMeBlush."
In support of the big 4-0, Reese has received a bonafide cavalcade of celebrity well-wishers and celebrators, from Chelsea Handler to Jennifer Aniston, Justin Theroux, Courteney Cox, Kate Hudson, Robert Downey Jr., Nicole Kidman, Keith Urban, Tobey Maguire, Jason Bateman and Matthew McConaughey, who attended the actresses' Hollywood birthday bash.
It's the kind of guest list that would even give Taylor Swift major squad goals, except, of course, the "Bad Blood" singer was there too to give a surprise performance.
Watch the video below.