The 49-year-old actress was at the awards show to present the Generations Award to actor Will Smith.
"What makes Will the voice of an entire generation? Why can he step into a ring and transform so easily into Ali? How can he capture the courage of a man who stood up to the NFL? It's because with every performance you see his soul and that same boundless spirit is evident not just on screen but in his family life and his charitable work as well," Berry said in tribute to her friend.
"The reason I admire this amazing, wonderful, talented man most," she continued, "is that he's a champion for diversity, blazing a path for actors by showing that someone of any color, any role and can open any movie and can win every award and be the biggest freakin' movie star in the whole world."
Diversity was also on Berry's mind during the recent #OscarsSoWhite controversy. Watch what she had to say in the video below.