"It was incredibly disturbing to hear someone that is up for the [presidency] of the United States talking about a teenage girl in the way that he did," the 57-year-old Golden Globe winner told ET's Lauren Zima at the Children's Hospital Los Angeles Once Upon a Time Gala on Saturday. "It was disgusting and she deserves people's support."
In a 12-year-old interview with Stern, Trump speculated about Lohan, then 18, saying that the actress was "probably deeply troubled and therefore great in bed."
"How dare anyone, let alone a man in that position, make comments like that when clearly she was having difficulties in her life," Curtis added, referring to Lohan's string of high-profile run-ins with the law over the course of several years.
The actress went on to say that Lohan's difficulties have "seemingly straightened out."
"She's doing beautiful relief work with children in Syria," Curtis shared. "She's in Athens right now. She is doing very well. I'm sorry that we all had to hear that and, then again, maybe it was helpful that we all heard it."
A representative for Lohan told CNN in an email that the 30-year-old actress has chosen to "disregard" the 12-year-old comments.
"Right now, Lindsay is choosing to focus on the positive things happening in her life and has decided to disregard the comments made about her by presidential nominee Donald Trump," the rep said. "She is focusing on helping children around the world in need and that's where her passion is."
"I believe that people will make the choice for someone whose experience will help this country," Curtis continued. "Because that's what we need right now. Experience, strength and hope for America. Not divisive, lewd, lascivious, disgusting, vile commentary from a misogynist."