Amy Schumer decided to read an open letter during her stand-up show at New York City's Madison Square Garden on Tuesday night that called out the Trump supporters who walked out of her show in Tampa, Florida.
On Sunday night in the Sunshine State, the Trainwreck star asked a Trump supporter to come onstage and explain why he was voting for the presidential hopeful. She also referred to Trump as an "orange, sexual-assaulting, fake-college-starting monster."
"Dearest Tampa, I’m sorry you didn’t want me, a comedian who talks about what she believes in, to mention the biggest thing going on in our country right now," Schumer read aloud to a cheering audience in NYC. "How could I think it was OK to spend five minutes having a peaceful conversation with someone with different views?"
WATCH: Amy Schumer Addresses Racial Inequality Controversy -- 'I Can’t Think of Anybody I’m Racist Against'
The 35-year-old comedian added, "After the show, I want you to know that I will go straight to a rehab facility that will teach me how to make all people happy."
Prior to hitting the stage on Tuesday evening, Schumer assured those attending that she would deliver a "squeaky clean show," calling it the "#TampaApologyTour."
Schumer's open letter wasn't the only new addition to her stand-up show. Madonna also surprised the crowd when she opened for her comedian friend. "So much fun opening up for @amyschumer at Madison Square Garden tonight!!" the 58-year-old singer Instagrammed. "It was short but it was sweet (like me). I'm forever changed! Love you Amy!!"
As fans may recall, Schumer opened for Madonna during her NYC shows in September 2015.
WATCH: Amy Schumer Adorably Covers 'Like a Prayer' as a Kid in Flashback Video
"Love and Respect this woman so much!!" Madonna posted on Tuesday night. "Thanks for letting me get on your stage! It was AWESOME!! @amyschumer"
Schumer also got the music icon to do a human pyramid with her pals, and shared the moment on Instagram.
The Tampa show wouldn't be the first time Schumer has butted heads with some of her audience members. During her performance in Stockholm, Sweden over the summer, the comedian had a guy booted out of her show after he heckled her by yelling, "Show me your t*ts!"
Check out Schumer's response: