It's not always easy being beautiful.
"Jobs with real gravitas go to people that are physically right for them and that's the end of the story," Theron says. "How many roles are out there for the gorgeous, f***ing, gown-wearing eight-foot model? When meaty roles come through, I've been in the room and pretty people get turned away first."
She also points out what she believes are the unfair beauty standards placed on women.
"We live in a society where women wilt and men age like fine wine," she says. "And, for a long time, women accepted it. We were waiting for society to change, but now we’re taking leadership. It would be a lie to say there is less worry for women as they get older than there is for men... It feels there's this unrealistic standard of what a woman is supposed to look like when she’s over 40."
That being said, it's safe to say that Theron, who turned 40 last August, is looking better than ever. The South African actress shows off her long legs on the super sexy cover of the men's magazine, going pants-less in nothing but a blazer and a black pair of stilettos.
The mother-of-two is currently single, after splitting from actor Sean Penn last June. Last month, she denied reports that she had "ghosted" the 55-year-old Oscar winner during their breakup -- meaning, she'd simply stopped responding to his calls.
"When you leave a relationship there has to be some f**king crazy story or some crazy drama. And the f**king ghosting thing, like literally, I still don't even know what it is," she told WSJ magazine. "It's just its own beast."