While detailing her experience, Applegate reveals that her health journey was a challenge.
"Shooting [Dead to Me] was the hardest thing I've ever had to do in my life," she said. "I was diagnosed during shooting and I didn't know what was happening to me. I couldn’t walk. They had to use a wheelchair to get me to set. I was freaking out until someone was like, 'You need a MRI.'"
She added, "Then I found out on a Monday after work that I had MS. A disease that I'm going to have for the rest of my life. And then I started thinking about the last four years and I had very small symptoms."
The Married with Children alum shared the importance of paying attention to your body, as she revealed that the symptoms where there before she was diagnosed with the illness.
"We were on set, and I would go, 'Oh, I think I'm tired,'" she said. "So it presented itself a few years ago until it just got as bad as it did."