Murphy -- who broke big as a cast member on Saturday Night Live in the early '80s -- made his big screen debut as one of the two leads in the classic crime dramedy 48 Hours. His first dozen films included the timeless comedy classics Trading Places, Beverly Hills Cop, and Coming to America.
In the 1990s, Murphy's career transitioned into the realm of family friendlier fare -- such as The Nutty Professor and Doctor Dolittle -- and he also became a beloved voice actor, lending his vocal talents to the Disney film Mulan, where he played the dragon Mushu, and voicing Donkey several times as part of the Shrek franchise.
In total, Murphy's films have over $6 billion at the box office, making him one of the most commercially successful actors in Hollywood. And top it all off with his 2007 Oscar nomination for his performance in Dreamgirls, for which he took home the Golden Globe.