The film producer was initially planning to go to Switzerland for sex addiction treatment.
Harvey Weinstein has headed off for treatment.
A source tells ET that the film producer has flown out of Los Angeles and is headed to Arizona to receive treatment amid his sexual harassment scandal.
According to the source, Weinstein was planning to go to Switzerland for treatment, but his brother, Bob, suggested he go to The Meadows in Arizona. While it's unclear if Weinstein will be checking into The Meadows, the source says he did follow his brother's advice and flew to Arizona.
Previous reports stated that Weinstein was planning to leave the country to seek treatment for sex addiction at a live-in facility overseas, however, a source told ET that his originally-planned trip was delayed due to "plane issues."
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While Weinstein prepares to begin treatment, a source close to his estranged wife, Georgina Chapman, told ET that she is "not doing well" since announcing on Tuesday that she plans to leave her husband in the wake of the accusations of sexual harassment and misconduct leveled against him.
"She is very upset and feels defeated," the source said. "She is not concerned about her own finances whatsoever."
The source added that Chapman, who is currently living in New York City, "always knew [Weinstein] exhibited questionable behavior," while the her estranged husband is "feeling very desperate and he is struggling."
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Weinstein was fired from The Weinstein Company on Sunday, after The New York Times' initial article on Thursday claimed he had sexually harassed women over three decades. More women, including Gwyneth Paltrow and Angelina Jolie, have since gone on the record accusing him of sexual harassment or sexual assault.
In a statement to ET, Weinstein's lawyer, Charles J. Harder, called the New York Times report "saturated with false and defamatory statements." He also said Weinstein and his team are planning to file a lawsuit, with any proceeds being donated to women's organizations.
On Tuesday, Weinstein's spokesperson, Sallie Hofmeister, added in a statement, "Mr. Weinstein has further confirmed that there were never any acts of retaliation against any women for refusing his advances... Mr. Weinstein obviously can’t speak to anonymous allegations, but with respect to any women who have made allegations on the record, Mr. Weinstein believes that all of these relationships were consensual. Mr. Weinstein has begun counseling, has listened to the community and is pursuing a better path."
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Reporting by Rande Iaboni.