Prepare for the 'Rise of the Planet of the Apes'

20th Century Fox

James Franco and 'Slumdog Millionaire' star Freida Pinto are faced with an ethical dilemma -- and the next step in evolution -- in 'Rise of the Planet of the Apes.' Watch the exciting trailer!

When Franco develops a miracle Alzheimer's cure that allows the brain to repair itself, he tests the serum on an ape who gives birth to a young chimp named Caesar (played by Andy Serkis, who provided the voice and body motion-capture for Gollum in 'The Lord of the Rings' as well as 'King Kong' himself). But when the serum's side-effects result in increased intelligence, mankind soon finds a rebellion on its hands: The rise of the Planet of the Apes.

Also starring Brian Cox and John Lithgow, 'Rise of the Planet of the Apes' is poised to conquer the box office August 5.