John C. Reilly voices the title character, a Donkey Kong-style bad guy who is growing tired of the repetitive nature of his hit game and being overshadowed by good guy Fix-It Felix (Jack McBrayer). Despite receiving encouragement in his video game bad guy support group, Ralph decides to change things up and exits the game, setting out on a game-hopping journey across the arcade to prove he's got what it takes to be a hero.
On his quest, he meets the tough-as-nails Sergeant Calhoun (Jane Lynch) from the first-person action game Hero's Duty and feisty misfit Vanellope von Schweetz (Sarah Silverman) in the candy-coated cart racing game Sugar Rush. But when Ralph accidentally unleashes a deadly enemy that threatens the entire arcade, can he realize his dream and save the day before it's too late?
Wreck-It Ralph crashes onto the big screen on November 2.