In the film, audiences will see Stephen go from a young scholar to a genius physicist confined to a wheelchair. Along the way he falls in love with a young woman named Jane Wilde (played by Felicity Jones) whom he married in 1965.
"They fell instantly in love with each other," said Felicity. "I think they challenged each other as well."
The couple's love for each other is tested when Stephen is diagnosed with the paralyzing degenerative disease ALS, for which the usually life expectancy is two years.
"It's so important to me to show the depths of giving that Jane had to have to keep helping Stephen," said Felicity.
"Their capacity to survive against all odds was quite an amazing thing," said Eddie, who played Marius in Les Miserables. "This extraordinary woman was the fuel behind a lot of his success. All these things make someone live a full life, and my God, has he lived a full life -- and continues to."
The Theory of Everything hits theaters November 7.