Sometimes reunions are a blast. But for Judy Greer, Natasha
Lyonne and Jessica St. Clair, things couldn’t be further from the truth.

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In Addicted to Fresno,
Shannon (Greer) and Martha (Lyonne) are two sisters that reunite after Shannon
gets out of rehab and start working at the same hotel. The two quickly find
themselves in trouble when Shannon accidentally kills one of the guests.

ET has an exclusive clip from the film that sets the tone
for this dark comedy. During a shift at work, Shannon and Martha bump into a high
school classmate, Kristen (played by Jessica St. Clair), who works at the front
desk. What should be a happy reunion quickly turns bitter when Shannon reveals
exactly what she’s been up to since high school -- and shares an unexpected secret.

The new film, directed by Jamie Babbit (But I’m a Cheerleader), stars Aubrey Plaza, Ron Livingston, Fred Armisen, and Molly Shannon.

Addicted to Fresno also serves as a special treat for But I’m a Cheerleader fans, reuniting the director with Lyonne and her on-screen lover, Clea DuVall.

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Addicted to Fresno debuts On Demand starting Sept. 1 and will be in select theaters on Oct. 2.