A source close to production describes the film as an "imaginative family comedy with heart" -- think Disney’s Enchanted or the Tom Hanks classic, Big -- and is the first of its kind to feature the timeless Mattel character. The movie is slated to be released next summer.
The plot involves Barbie getting kicked out of Barbieland for not being "perfect enough," and embarking on an adventure in the real world.
Lauren Abrahams, senior vice president of production, will oversee the project for Sony Pictures.
Appealing to a PG audience will be somewhat new territory for Schumer, whose breakout film was the R-rated comedy Trainwreck.
However, Mattel has previously received criticism for the doll's unrealistic figure, and Schumer taking on the Barbie role could be a nice fit.
As a major proponent of body confidence, Schumer had no problem calling out Glamour magazine for including her in its plus-size issue earlier in the year.
"I think there's nothing wrong with being plus size. Beautiful healthy women," Schumer vented on Instagram at the time, sharing a snapshot of the "Women Who Inspire Us" article featuring celebs deemed “Chic At Any Size!”
"Plus size is considered size 16 in America," Schumer noted before revealing what size she wears. “I go between a size 6 and an 8. @glamourmag put me in their plus size only issue without asking or letting me know and it doesn't feel right to me."
The magazine later clarified to that the special edition issue was “aimed at women size 12 and up,” and did not describe Schumer as “plus-size.”
“We believe her passionate and vocal message of body positivity IS inspiring, as is the message of the many other women, of all sizes, featured,” a spokesperson told ET in a statement, adding, “We are sorry if we offended her in any way."