Actor Pierce Brosnan spoke about losing his loved ones at the Stand Up To Cancer telethon last night.
PHOTOS: Stars at 2014 SU2C
Having lost both his first wife Cassandra Harris and daughter Charlotte Brosnan to the disease, he called it "insidious."
He said, "To watch someone you love have his or her life eaten away bit by bit by this insidious disease, that part of your sorrow becomes an indelible part of your psyche. I held the generous, strong, beautiful hand of my first wife Cassie as ovarian cancer took her life much too soon. Just last year, I held the hand of my funny, wonderful daughter Charlotte before she, too, died from this wretched inherited disease."
Pierce also announced that Stand Up to Cancer will be putting together an ovarian cancer dream team.
Held at the Dolby Theatre in Los Angeles, Pierce was joined by celebrities including Jennifer Aniston, Halle Berry, Reese Witherspoon, Gwyneth Paltrow, Jon Hamm, Will Ferrell, Jesse Tyler Ferguson and more.
Ariana Grande was there to perform for her late grandfather who passed away from cancer. Lupe Fiasco, Common, Jennifer Hudson, Dave Matthews and The Who also performed.
NEWS: Ariana Grande Opens Up About Her Late Grandfather
This year, celebrities used an on-stage digital lounge to interact with viewers through social media. Viewers were able to donate by calling and texting.
According to Standup2cancer.org, "1 in 2 men and 1 in 3 women will be diagnosed with cancer in their lifetimes."
By have the celebrity attention, SU2C is able to generate more awareness and raise funds quickly. One hundred percent of the donations will go to support collaborative cancer research programs.
Watch Pierce Brosnan share his memories of the late, great Robin Williams below.