After Jenner's interview with Sawyer in April, Humphries -- who was famously married to Kardashian for 72 days before she filed for divorce -- tweeted: "Man, I'm glad I got out when I did. #Gottadoyou."
The 30-year-old athlete later clarified and apologized for his comments in another tweet, but Jenner didn't forget it.
"Kris... idiot Humphries tweets, 'Thank God I got out of that family in time.' And just got absolutely ripped, just ripped," she tells Disick. "To the point that four hours later, he had to apologize."
Jenner also asks Disick to tell her from a "man's perspective" how he feels about her gender transition.
"I definitely think it's a lot different for me than a buddy you know because the sense that you've been in my life a long time," Kourtney Kardashian's ex explains. "You're part of my kids' life. I don't know if every man in the world is going to be as comfortable as I am."
While Jenner is not so happy with Humphries, she was thrilled about what an artist did to the death threats and hate tweets the reality star received after her Vanity Fair spread. Connor Collins used the messages to make a portrait of Jenner's VF cover.
"Turning hate into love is so beautiful and powerful - great job by this artist," Jenner said of Collins' work.
"You're sensitive and amazing to all these new people in your life, you're just not so sensitive and amazing to the family that you left behind," she says, tearing up. "When you feel like you gave your whole life to somebody and the sum of it all was you were a distraction..."