The pretty pair, who have been married for almost three years, will be honored with the Inspiration Award for their work with the LGBT community at GLSEN's Respect Awards on Friday, Oct. 23 in Beverly Hills, California.
Timberlake, 34, and Biel, 33, are "two vocal and committed allies to the LGBT community who are also devoted to charitable works that improve the lives of youth," GLSEN Executive Director Dr. Eliza Byard said in a statement.
She further added that they "have consistently been visible and committed allies."
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Receiving this award will be another bright moment for the couple's already big year.
In April, they welcomed son Silas Randall, and before his arrival, the "Mirrors" singer sweetly posted a pic of his wife's baby bump, writing, "the greatest gift ever."
The happy duo will be in good company when they accept their award as they join past honorees Bob Greenblatt, Marilyn and Jeffrey Katzenberg, Jim Parsons and Todd Spiewak, and Julia Roberts and Danny Moder.