EXCLUSIVE: Meghan Trainor to Perform Medley, Luke Bryan to Debut Single at American Music Awards

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Charlie Puth and Karen Fairchild will also join the show.

It's official: Meghan Trainor is headed to the American Music Awards stage -- and so is Luke Bryan!

Trainor and Bryan are both up for several awards at this year's ceremony, including the coveted Artist of the Year honor, and now ET can exclusively confirm that they'll each perform.

Trainor will sing a special medley of her brand new single, "Like I'm Gonna Lose You," before she's joined onstage by Charlie Puth for their duet, "Marvin Gaye." Separately, Bryan will debut his new single, "Home Alone Tonight," alongside Little Big Town's Karen Fairchild.

WATCH: Meghan Trainor's New Music Is Inspired By Her 'Curves' and Dad's Killer Dance Moves 

Trainor hinted at the performance during a recent sit-down interview with ET.

"It's still a shock," she said on Oct. 20 of her multiple nominations. "I still just signed up! I still just got here! And I thought, especially because of [vocal cord] surgery, I've been gone, I've been home chilling. I figured [with] the award shows -- I'm not even gonna go to this year. But I'm there, I'm nominated. I'm gonna perform, hopefully."

Jennifer Lopez has also been tapped to perform and host the ceremony this year, airing live on Sunday, Nov. 22, at 8 p.m. ET on ABC. The show will mark a bit of a reunion between Trainor and Lopez, who previously offered up some sage advice to the newcomer. The pair met at the AMAs in 2014.

WATCH: Meghan Trainor Reveals J.Lo's Dating Advice

"I was star struck the whole time," Trainor previously told ET. "I told her Selena the movie was the reason I wanted to become a singer, and then I asked her a bunch of questions like how do you have boyfriends in this industry?"

Lopez's response: "Be very picky."

Additional performers at the AMAs include 5 Seconds of Summer, Selena Gomez, Nick Jonas, Demi Lovato, One Direction, Carrie Underwood and Walk the Moon.

While you wait for the festivities, find out what Trainor has been cooking up in the studio for her sophomore album in ET's interview, below.