"We're just really good friends and we talk about everything, and we never ever, ever lie to each other, like, not even the tiniest lies," the Scandal star said about the secret to maintaining their longtime relationship, especially amid last summer's string of celeb splits. "And she's the only person I want to hang out with. Like, she is my best friend and I just want to be with her all the time."
"She's just so awesome!" she added. "Who wouldn't want to be with Ellen all the time?"
In September, the 57-year-old comedian slammed tabloid reports that the two were breaking up. DeGeneres and de Rossi have been dating since 2004, and tied the knot in 2008, after the overturn of the same-sex marriage ban in California.
"We really don't almost break up, we don't fight, we're madly in love, and I guess it's boring," DeGeneres told Howard Stern on his SiriusXM radio show.
But de Rossi's relationship wasn't all the former Ally McBeal actress opened up about at the star-studded bash over the weekend. The actress also gave us the scoop on the couple's recent holiday vacation, when the two were photographed with rumored new item Harry Styles and Kendall Jenner in the Caribbean.
"We just talked and hung out for a little bit, and they're lovely people and we just had fun," de Rossi said. "They're really great. I love Harry especially, and I'm just getting to know Kendall, but you know, they're great."
When ET caught up with DeGeneres at the People's Choice Awards last Wednesday, the talk show host might have insinuated that the two young stars are romantically involved, though Styles and Jenner have never confirmed anything about their relationship.