The sixth time's a charm!

Leonardo DiCaprio won Best Actor for The Revenant at the 2016 Oscars, marking the 41-year-old's first victory at the awards show.

After a standing ovation, Leo graciously accepted his award, saying "The Revenant was a product of the unbelievable cast and crew."

Striking a more serious tone, the Oscar winner used much of his acceptance speech to address the issue of climate change, saying, "Making The Revenant was about man's relationship to the natural world."

"Climate change is real, it is the most urgent threat facing our species," he added. "Let us not take this planet for granted. I do not take tonight for granted."

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After the show, Kanye West congratulated Leo on his big win, writing, "Finally!!! Our guy!!! We're so so happy for Leo!!!"

"He deserves it," Revenant director Alejandro Inarritu told ET before the show. I didn't give it to him. I think he got it, hopefully, and if not, his work is already a testament to how good he is."

"But I hope this night he gets what he's really deserved a long time," the director added.

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Inarritu also won the directing Oscar for the film, his second.

Recently, Leo praised Revenant cinematographer Emmanuel Lubezki -- who won the cinematography Oscar this year -- his third consecutive -- for creating a film that is "groundbreaking cinematically."

The Revenant won 3 Oscars, getting upset for best picture by Spotlight.

MORE: Oscars 2016: See the Complete Winners List!

Congrats, Leo!

Watch the video below to see the road to his victory.